Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury
- Author(s): Willenbring, Holger
- Schaub, J
- Malato, Y
- Gormond, C
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4376310?pdf=render
Hepatocytes provide most liver functions, but they can also proliferate and regenerate the liver after injury. However, under some liver injury conditions, particularly chronic liver injury where hepatocyte proliferation is impaired, liver stem cells (LSCs