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Phosphatidic acid: a lipid regulator of the Hippo pathway
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https://doi.org/10.1080/23723556.2018.1558683Abstract
The Hippo pathway, a signaling pathway highly conserved across species, plays a crucial role in organ size control and cancer suppression. Our recent study shows that phosphatidic acid can regulate the Hippo pathway through a physical lipid-protein interaction, providing additional insights into the Hippo-related tissue homeostasis and cancer development.
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