Understanding the role of transport velocity in biomotor-powered microtubule spool assembly
- Author(s): Tan, AJ
- Chapman, DE
- Hirst, LS
- Xu, J
- et al.
Published Web Locationhttps://doi.org/10.1039/c6ra19094d
We examined the sensitivity of microtubule spools to transport velocity. Perhaps surprisingly, we determined that the steady-state number and size of spools remained constant over a seven-fold range of velocities. Our data on the kinetics of spool assembly further suggest that the main mechanisms underlying spool growth vary during assembly.