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Understanding the role of transport velocity in biomotor-powered microtubule spool assembly

  • Author(s): Tan, AJ;
  • Chapman, DE;
  • Hirst, LS;
  • Xu, J
  • et al.
Abstract

We examined the sensitivity of microtubule spools to transport velocity. Perhaps surprisingly, we determined that the steady-state number and size of spools remained constant over a seven-fold range of velocities. Our data on the kinetics of spool assembly further suggest that the main mechanisms underlying spool growth vary during assembly.

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