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Open Access Publications from the University of California

Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging

  • Author(s): Gartner, Zev
  • Sogi, KM
  • Gartner, ZJ
  • Breidenbach, MA
  • Appel, MJ
  • Schelle, MW
  • Bertozzi, CR
  • et al.

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The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb's single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate-dependent

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