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Open Access Publications from the University of California

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

  • Author(s): Criswell, Lindsey
  • Molineros, JE
  • Maiti, AK
  • Sun, C
  • Looger, LL
  • Han, S
  • Kim-Howard, X
  • Glenn, S
  • Adler, A
  • Kelly, JA
  • Niewold, TB
  • et al.

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Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with a strong genetic component. African-Americans (AA) are at increased risk of SLE, but the genetic basis of this risk is largely unknown. To identify causal variants in SLE loci in

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