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Enhancer dysfunction: how the main regulators of gene expression contribute to cancer.
- Author(s): Kurdistani, Siavash K
- et al.
Published Web Locationhttps://doi.org/10.1186/gb-2012-13-5-156
A genome-wide epigenetic analysis of enhancer elements in colon cancer has implicated distal gene regulatory DNA sequences in the establishment of an oncogenic transcriptional program.