Research Grants Program Office (RGPO)
Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy.
- Author(s): Hoenigl, Martin
- de Oliveira, Michelli Faria
- Pérez-Santiago, Josué
- Zhang, Yonglong
- Woods, Steven Paul
- Finkelman, Malcolm
- Gianella, Sara
- et al.
Published Web Locationhttps://doi.org/10.3205/id000018
We evaluated associations between levels of BDG and other biomarkers of inflammation in blood from 41 virologically suppressed persons with chronic HIV-infection. We found a significant correlation between BDG and neopterin levels (r=0.68), and trends to significance for correlations with other inflammation markers (tumor-necrosis-factor-α: r=0.30; interleukin-8: r=0.30; interleukin-6: r=0.28). In conclusion, BDG levels correlated with inflammation markers in a cohort of virologically suppressed individuals with chronic HIV infection. Future studies are needed to evaluate whether BDG may be a marker for morbidity in chronic HIV infection.