Lawrence Berkeley National Laboratory

Comparison of whole-genome assemblies is required at all stages of their completion and analysis ? from individual reads to draft and finished genomes, from assembly through finishing and annotation. We have expanded the VISTA suite of tools for comparative genomics by adding a novel interactive web application, the VISTA Synteny Viewer (VSV), for the navigation of whole genome alignments at multiple levels of resolution. The VSV uses modern web technologies to tightly wed the visualization of DNA synteny at the level of whole genomes, individual chromosomes/scaffolds, and individual aligned loci, as well to dynamically generate dot plots.