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Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung

  • Author(s): Looney, Mark
  • Krummel, Matthew
  • Sheppard, Dean
  • Locksley, Richard
  • Thornton, EE
  • Looney, MR
  • Bose, O
  • Sen, D
  • Huang, X
  • Krummel, MF
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3371730?pdf=render
No data is associated with this publication.
Abstract

Asthma pathogenesis is focused around conducting airways. The reasons for this focus have been unclear because it has not been possible to track the sites and timing of antigen uptake or subsequent antigen presentation to effector T cells. In this study, w

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