Skip to main content
eScholarship
Open Access Publications from the University of California

Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor.

  • Author(s): Sanders, Lauren M
  • Rangaswami, Arun
  • Bjork, Isabel
  • Lam, Du Linh
  • Beale, Holly C
  • Kephart, Ellen Towle
  • Durbin, Ann
  • Learned, Katrina
  • Currie, Rob
  • Lyle, A Geoffrey
  • Pfeil, Jacob
  • Shah, Avanthi Tayi
  • Lee, Alex G
  • Leung, Stanley G
  • Behroozfard, Inge H
  • Breese, Marcus R
  • Peralez, Jennifer
  • Hazard, Florette K
  • Lacayo, Norman
  • Spunt, Sheri L
  • Haussler, David
  • Salama, Sofie R
  • Sweet-Cordero, E Alejandro
  • Vaske, Olena M
  • et al.
Abstract

Gliomatosis peritonei is a rare pathologic finding that is associated with ovarian teratomas and malignant mixed germ cell tumors. The occurrence of gliomatosis as a mature glial implant can impart an improved prognosis to patients with immature ovarian teratoma, making prompt and accurate diagnosis important. We describe a case of recurrent immature teratoma in a 10-yr-old female patient, in which comparative analysis of the RNA sequencing gene expression data from the patient's tumor was used effectively to aid in the diagnosis of gliomatosis peritonei.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
Current View