Naltrexone improves learning and attention in self-injurious individuals with developmental disabilities
Abstract
In the primary study, 10 patients were enrolled in a 10-week double-blind evaluation of the effectiveness of naltrexone in reducing self-injurious behavior (SIB) in adults with developmental disabilities. Within this study, the effects of naltrexone on acquisition of a paired associates task were investigated. The effects of three doses of naltrexone (0.5, 1.0, and 2.0 mg/kg orally) were tested on separate weeks. Learning evaluations were conducted on Wednesday of each week. Naltrexone improved measures of independence and attention, and decreased trial rate. © 1993 Plenum Publishing Corporation.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.