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Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake

  • Author(s): Verkman, Alan
  • Hara-Chikuma, M
  • Chikuma, S
  • Sugiyama, Y
  • Kabashima, K
  • Verkman, AS
  • Inoue, S
  • Miyachi, Y
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3457725?pdf=render
No data is associated with this publication.
Abstract

Chemokine-dependent trafficking is indispensable for the effector function of antigenexperienced T cells during immune responses. In this study, we report that the water/glycerol channel aquaporin-3 (AQP3) is expressed on T cells and regulates their traffi

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