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Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in rats

  • Author(s): Verkman, Alan
  • Cil, O
  • Esteva-Font, C
  • Tas, ST
  • Su, T
  • Lee, S
  • Anderson, MO
  • Ertunc, M
  • Verkman, AS
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4523423?pdf=render
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Abstract

© 2015 International Society of Nephrology Inhibitors of kidney urea transporter (UT) proteins have potential use as salt-sparing diuretics (‘urearetics’) with a different mechanism of action than diuretics that target salt transporters. To study UT inhibi

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