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Pre-term infants exhibit impaired prediction and learning in Audio-Visualassociation paradigm

Abstract

Forming reliable predictions about upcoming events are both essential to and the product of successful learning.Using fNIRS recording of cortical hemodynamics, we measured infants’ prediction of upcoming visual events that were pre-ceded by auditory cues in infants who are at-risk for poor development due to premature birth and their full-term peers. Wecompared prediction and learning across groups by fitting their occipital cortex response (which we assumed to reflect themagnitude of the prediction error) to a reinforcement learning model with a dynamic learning rate. We found that preemies hada lower learning rate than full-terms. These findings shed light on the origins of the developmental difficulties associated withprematurity.

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