An Assay Suitable for High Throughput Screening of Anti-Influenza Drugs
- Author(s): Degrado, William
- Mao, L
- Wang, J
- DeGrado, WF
- Inouye, M
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3542334?pdf=render
We developed a novel drug screening system for anti-influenza A virus by targeting the M2 proton channel. In the SPP (Single Protein Production) system, E. coli cell growth occurs only in the presence of effective M2 channel inhibitors, and thus simple mea
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