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PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma

  • Author(s): Grandis, Jennifer;
  • Chiosea, SI;
  • Grandis, JR;
  • Lui, VWY;
  • Diergaarde, B;
  • Maxwell, JH;
  • Ferris, RL;
  • Kim, SW;
  • Luvison, A;
  • Miller, M;
  • Nikiforova, MN
  • et al.

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Background: Recent genomic evidence suggests frequent phosphatidylinositide 3-kinase (PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma. Mutations/amplification of the gene encoding p110α catalytic subuni

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