Targeted Therapy for MAPK Alterations in Pediatric Gliomas.
- Author(s): Nicolaides, Theodore
- Truong, AY
- Nicolaides, TP
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4627711?pdf=render
Although the mitogen-activated protein kinase (MAPK) pathway helps promote normal cell development, the pathway is known to contribute to the initiation and growth of many types of cancers. Tumorigenesis can result from mutations in a number of the pathway