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TorsinA regulates the LINC to moving nuclei.

  • Author(s): Starr, Daniel A;
  • Rose, Lesilee S
  • et al.
Abstract

How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polarization by mediating the dynamics of LINC complexes.

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