TorsinA regulates the LINC to moving nuclei.
- Author(s): Starr, Daniel A
- Rose, Lesilee S
- et al.
Published Web Locationhttps://doi.org/10.1083/jcb.201701054
How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polarization by mediating the dynamics of LINC complexes.