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Fix it, dont trash it: Ribosome maintenance by chaperone-mediated repair of damaged subunits.

Abstract

Acute stressors or normal cellular function may result in ribosomal protein damage, which threatens the functional ribosome pool and translation. In this issue, Yang et al.1 show that chaperones can extract damaged ribosomal proteins and replace them with newly synthesized versions to repair mature ribosomes.

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