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Convective washout reduces the antidiarrheal efficacy of enterocyte surface-targeted antisecretory drugs
Published Web Location
http://europepmc.org/articles/PMC3557305?pdf=renderNo data is associated with this publication.
Abstract
Secretory diarrheas such as cholera are a major cause of morbidity and mortality in developing countries. We previously introduced the concept of antisecretory therapy for diarrhea using chloride channel inhibitors targeting the cystic fibrosis transmembra
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