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An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

Published Web Location

http://europepmc.org/articles/PMC3521494?pdf=render
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Abstract

People with pale skin, red hair, freckles and an inability to tan - the 'red hair/fair skin' phenotype - are at highest risk of developing melanoma, compared to all other pigmentation types. Genetically, this phenotype is frequently the product of inactiva

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