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CYP2A6 genotype but not age determines cotinine half-life in infants and children

Published Web Location

http://europepmc.org/articles/PMC3820275?pdf=render
No data is associated with this publication.
Abstract

The formation of cotinine, the main proximate metabolite and a biomarker of nicotine exposure, is mediated primarily by cytochrome P450 (CYP)2A6. Our aim was to determine whether higher cotinine levels in young children exposed to secondhand smoke (SHS) ar

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