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Human body epigenome maps reveal noncanonical DNA methylation variation
- Schultz, Matthew D;
- He, Yupeng;
- Whitaker, John W;
- Hariharan, Manoj;
- Mukamel, Eran A;
- Leung, Danny;
- Rajagopal, Nisha;
- Nery, Joseph R;
- Urich, Mark A;
- Chen, Huaming;
- Lin, Shin;
- Lin, Yiing;
- Jung, Inkyung;
- Schmitt, Anthony D;
- Selvaraj, Siddarth;
- Ren, Bing;
- Sejnowski, Terrence J;
- Wang, Wei;
- Ecker, Joseph R
Published Web Location
https://doi.org/10.1038/nature14465Abstract
As part of the Epigenome Roadmap Project, genome-wide maps of DNA methylation and transcriptomes together with genomic DNA sequencing of 18 different primary human tissue types from 4 individuals are presented; analysis reveals widespread differential methylation of CG sites between tissues, and the presence of non-CG methylation in adult tissues.
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