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Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE.

  • Author(s): Zamvil, Scott
  • Shetty, A
  • Gupta, SG
  • Varrin-Doyer, M
  • Weber, MS
  • Prod'homme, T
  • Molnarfi, N
  • Ji, N
  • Nelson, PA
  • Patarroyo, JC
  • Schulze-Topphoff, U
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4202928?pdf=render
No data is associated with this publication.
Abstract

Studies evaluating T-cell recognition of myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis (MS) and its model, experimental autoimmune encephalomyelitis (EAE), have focused mostly on its 117 amino acid (aa) extracellular domain, especially pe

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