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High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
- Yu, Channing;
- Mannan, Aristotle M;
- Yvone, Griselda Metta;
- Ross, Kenneth N;
- Zhang, Yan-Ling;
- Marton, Melissa A;
- Taylor, Bradley R;
- Crenshaw, Andrew;
- Gould, Joshua Z;
- Tamayo, Pablo;
- Weir, Barbara A;
- Tsherniak, Aviad;
- Wong, Bang;
- Garraway, Levi A;
- Shamji, Alykhan F;
- Palmer, Michelle A;
- Foley, Michael A;
- Winckler, Wendy;
- Schreiber, Stuart L;
- Kung, Andrew L;
- Golub, Todd R
Published Web Location
https://doi.org/10.1038/nbt.3460Abstract
A method called PRISM rapidly identifies drug candidates that are effective against specific cancer cell lines.
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