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Ultraviolet A-induced cathepsin K expression is mediated via MAPK/AP-1 pathway in human dermal fibroblasts

  • Author(s): Maibach, Howard
  • Xu, Q
  • Hou, W
  • Zheng, Y
  • Liu, C
  • Gong, Z
  • Lu, C
  • Lai, W
  • Maibach, HI
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4105408?pdf=render
No data is associated with this publication.
Abstract

Background: Cathepsin K (CatK), a cysteine protease with the potent elastolytic activity, plays a predominant role in intracellular elastin degradation in human dermal fibroblasts (HDFs), and contributes to solar elastosis. In previous studies, CatK expres

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