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Proton release from the histidine-tetrad in the M2 channel of the influenza A virus

  • Author(s): Degrado, William
  • Dong, H
  • Fiorin, G
  • Degrado, WF
  • Klein, ML
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4226308?pdf=render
No data is associated with this publication.
Abstract

© 2014 American Chemical Society.The activity of the M2 proton channel of the influenza A virus is controlled by pH. The tautomeric state and conformation of His37, a key residue in the M2 transmembrane four-helix bundle, controls the gating of the channel

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