ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function
- Author(s): Debnath, Jayanta;
- Murrow, L;
- Malhotra, R
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4344874?pdf=render
© 2015 Macmillan Publishers Limited.The ubiquitin-like molecule ATG12 is required for the early steps of autophagy. Recently, we identified ATG3, the E2-like enzyme required for LC3 lipidation during autophagy, as an ATG12 conjugation target. Here, we demo