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Computational Protein Design Quantifies Structural Constraints on Amino Acid Covariation
Published Web Location
http://europepmc.org/articles/PMC3828131?pdf=renderNo data is associated with this publication.
Abstract
Amino acid covariation, where the identities of amino acids at different sequence positions are correlated, is a hallmark of naturally occurring proteins. This covariation can arise from multiple factors, including selective pressures for maintaining prote
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