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Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace.

  • Author(s): Qu, Kun
  • Garamszegi, Sara
  • Wu, Felix
  • Thorvaldsdottir, Helga
  • Liefeld, Ted
  • Ocana, Marco
  • Borges-Rivera, Diego
  • Pochet, Nathalie
  • Robinson, James T
  • Demchak, Barry
  • Hull, Tim
  • Ben-Artzi, Gil
  • Blankenberg, Daniel
  • Barber, Galt P
  • Lee, Brian T
  • Kuhn, Robert M
  • Nekrutenko, Anton
  • Segal, Eran
  • Ideker, Trey
  • Reich, Michael
  • Regev, Aviv
  • Chang, Howard Y
  • Mesirov, Jill P
  • et al.
Abstract

Complex biomedical analyses require the use of multiple software tools in concert and remain challenging for much of the biomedical research community. We introduce GenomeSpace (http://www.genomespace.org), a cloud-based, cooperative community resource that currently supports the streamlined interaction of 20 bioinformatics tools and data resources. To facilitate integrative analysis by non-programmers, it offers a growing set of 'recipes', short workflows to guide investigators through high-utility analysis tasks.

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