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Open Access Publications from the University of California

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

  • Author(s): Bankiewicz, Krzysztof
  • Salegio, EA
  • Streeter, H
  • Dube, N
  • Hadaczek, P
  • Samaranch, L
  • Kells, AP
  • Sebastian, WS
  • Zhai, Y
  • Bringas, J
  • Xu, T
  • et al.

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When nanoparticles/proteins are infused into the brain, they are often transported to distal sites in a manner that is dependent both on the characteristics of the infusate and the region targeted. We have previously shown that adeno-associated virus (AAV)

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