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Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

  • Author(s): Debnath, Jayanta
  • Haller, M
  • Hock, AK
  • Giampazolias, E
  • Oberst, A
  • Green, DR
  • Ryan, KM
  • Vousden, KH
  • Tait, SWG
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4502749?pdf=render
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Abstract

© Martina Haller, Andreas K Hock, Evangelos Giampazolias, Andrew Oberst, Douglas R Green, Jayanta Debnath, Kevin M Ryan, Karen H Vousden, and Stephen W G Tait.During macroautophagy, conjugation of ATG12 to ATG5 is essential for LC3 lipidation and autophago

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