Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib
- Author(s): Alexandru, D
- Van Horn, DK
- Bota, DA
- et al.
Published Web Locationhttps://doi.org/10.1007/s11060-009-0096-x
Radiation-induced midbrain fibrosarcoma is a rare, highly aggressive tumor, which is associated with poor prognosis. We present the case of a 48-year old man with brainstem fibrosarcoma 20 years following radiation therapy received for a pituitary tumor. We discuss this case in the context of the diagnostic criteria for these tumors, and previous reports of secondary and primary sarcomas of the central nervous system. © The Author(s) 2009.