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Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer.

  • Author(s): Diederich, Christian
  • Hsu, I-Chow
  • Zagar, TM
  • Vujaskovic, Z
  • Formenti, S
  • Rugo, H
  • Muggia, F
  • O'Connor, B
  • Myerson, R
  • Stauffer, P
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4162656?pdf=render
No data is associated with this publication.
Abstract

Unresectable chest wall recurrences of breast cancer (CWR) in heavily pretreated patients are especially difficult to treat. We hypothesised that thermally enhanced drug delivery using low temperature liposomal doxorubicin (LTLD), given with mild local hyp

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