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The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable
- Author(s): Fletterick, Robert
- Benod, C
- Villagomez, R
- Filgueira, CS
- Hwang, PK
- Leonard, PG
- Poncet-Montange, G
- Rajagopalan, S
- Fletterick, RJ
- Gustafsson, JA
- Webb, P
- et al.
Published Web Location
http://europepmc.org/articles/PMC4060991?pdf=renderNo data is associated with this publication.
Abstract
Nuclear receptors (NRs) are an important group of ligand-dependent transcriptional factors. Presently, no natural or synthetic ligand has been identified for a large group of orphan NRs. Small molecules to target these orphan NRs will provide unique resour
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