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The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable

  • Author(s): Fletterick, Robert
  • Benod, C
  • Villagomez, R
  • Filgueira, CS
  • Hwang, PK
  • Leonard, PG
  • Poncet-Montange, G
  • Rajagopalan, S
  • Fletterick, RJ
  • Gustafsson, JA
  • Webb, P
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4060991?pdf=render
No data is associated with this publication.
Abstract

Nuclear receptors (NRs) are an important group of ligand-dependent transcriptional factors. Presently, no natural or synthetic ligand has been identified for a large group of orphan NRs. Small molecules to target these orphan NRs will provide unique resour

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