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Double Trouble: HIV Latency and CTL Escape
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https://doi.org/10.1016/j.chom.2015.01.008Abstract
HIV can enter a state of latency that allows it to persist for decades in antiretroviral drug-treated patients. In a recent Nature paper, Deng et al. (2015) show that this latent reservoir also contains a large number of cytotoxic T lymphocyte escape mutants, presenting another challenge to HIV cure efforts.
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