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Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: Pharmacokinetics and correlation with digital perfusion

  • Author(s): Boin, Francesco
  • Shah, AA
  • Schiopu, E
  • Hummers, LK
  • Wade, M
  • Phillips, K
  • Anderson, C
  • Wise, R
  • Seibold, JR
  • Wigley, F
  • et al.

Published Web Location

http://europepmc.org/articles/PMC5011881?pdf=render
No data is associated with this publication.
Abstract

Introduction: Treprostinil diethanolamine is an innovative salt form of the prostacyclin analogue, treprostinil sodium, developed as an oral sustained release (SR) osmotic tablet. The availability of a formulation permitting convenient systemic delivery mi

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