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Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: Pharmacokinetics and correlation with digital perfusion
- Author(s): Boin, Francesco
- Shah, AA
- Schiopu, E
- Hummers, LK
- Wade, M
- Phillips, K
- Anderson, C
- Wise, R
- Seibold, JR
- Wigley, F
- et al.
Published Web Location
http://europepmc.org/articles/PMC5011881?pdf=renderNo data is associated with this publication.
Abstract
Introduction: Treprostinil diethanolamine is an innovative salt form of the prostacyclin analogue, treprostinil sodium, developed as an oral sustained release (SR) osmotic tablet. The availability of a formulation permitting convenient systemic delivery mi
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