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Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells

  • Author(s): Jablons, David
  • You, B
  • Yang, YL
  • Xu, Z
  • Dai, Y
  • Liu, S
  • Mao, JH
  • Tetsu, O
  • Li, H
  • Jablons, DM
  • You, L
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4414195?pdf=render
No data is associated with this publication.
Abstract

Alterations of the EGFR/ERK and Hippo/YAP pathway have been found in nonsmall cell lung cancer (NSCLC). Herein, we show that ERK1 and ERK2 have an effect on the Hippo/YAP pathway in human NSCLC cells. Firstly, inhibition of ERK1/2 by siRNA or small-molecul

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