Skip to main content
eScholarship
Open Access Publications from the University of California
Refine Search

UC Merced

UC Merced Previously Published Works bannerUC Merced

Radical Benzylation of Quinones via C-H Abstraction.

  • Author(s): Galloway, Jordan D;
  • Mai, Duy N;
  • Baxter, Ryan D
  • et al.

Published Web Location

https://doi.org/10.1021/acs.joc.9b01004
Abstract

Herein we report the development of radical benzylation reactions of quinones using Selectfluor and catalytic Ag(I) initiators. The reaction is believed to proceed via a C-H abstraction mechanism after Ag(I)-mediated reduction of Selectfluor. This reaction occurs under mild conditions and is effective for a variety of quinones and radical precursors bearing primary benzylic carbons. The use of preformed Ag(4-OMePy)2NO3 as a catalyst proved effective in improving the reaction efficiency by reducing unwanted degradation pathways available to Selectfluor.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
For improved accessibility of PDF content, download the file to your device.
Current View


Top