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Protein Complexes: Breaking Up Is Hard to Do Well
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https://doi.org/10.1016/j.str.2013.07.013Abstract
Mass spectrometry of protein assemblies reveals size and stoichiometry. In this issue of Structure, Hall and colleagues demonstrate that gas-phase dissociations can recapitulate solution structure for complexes with few intersubunit salt bridges, high charge density, inflexible subunits, or small intersubunit interfaces.
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