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Primary plasma cell leukemia: autologous stem cell transplant in an era of novel induction drugs
- Gowda, Lohith;
- Shah, Mithun;
- Badar, Ifra;
- Bashir, Qaiser;
- Shah, Nina;
- Patel, Krina;
- Kanagal-Shamanna, Rashmi;
- Mehta, Rohtesh;
- Weber, Donna M;
- Lee, Hans C;
- Manasanch, Elisabet E;
- Shah, Abdul;
- Thomas, Sheeba K;
- Parmar, Simrit;
- Nieto, Yago;
- Orlowski, Robert Z;
- Champlin, Richard;
- Qazilbash, Muzaffar H
- et al.
Published Web Location
https://doi.org/10.1038/s41409-018-0392-1Abstract
Primary plasma cell leukemia (pPCL) is a rare and aggressive variant of multiple myeloma (MM) with poor long-term survival after cytotoxic chemotherapy. Many novel drugs have revolutionized the treatment algorithms for MM. The impact of targeted therapy, both pre- and post-autologous stem cell transplant (auto-HCT) remains an area of ongoing interest. In this study, we report outcomes post auto-HCT for pPCL and the impact of maintenance therapy posttransplant with novel agents.
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