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Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

Published Web Location

http://europepmc.org/articles/PMC3493452?pdf=render
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Abstract

Genetic case-control association studies often include data on clinical covariates, such as body mass index (BMI), smoking status, or age, that may modify the underlying genetic risk of case or control samples. For example, in type 2 diabetes, odds ratios

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