Covalent, sequence-specific attachment of long DNA molecules to a surface using DNA-templated click chemistry
- Author(s): Abel, GR
- Cao, BH
- Hein, JE
- Ye, T
- et al.
Published Web Locationhttps://doi.org/10.1039/c4cc02900c
We present a novel method that covalently and sequence-specifically attaches long DNA molecules to a surface that is compatible with high-resolution atomic force microscopy (AFM) imaging. Surfaces prepared with this approach are ideally suited for performing biophysical experiments on single DNA molecules. This journal is © the Partner Organisations 2014.
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