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Open Access Publications from the University of California

Quantitative bi-component T2* Analysis of histologically normal achilles tendons

  • Author(s): Chang, EY
  • Du, J
  • Statum, S
  • Pauli, C
  • Chung, CB
  • et al.

© 2015, Muscles, Ligaments and Tendons Journal. All right reserved. Introduction: the aim of this pilot study was to implement ultrashort echo time (UTE) MRI with bicomponent analysis on grossly normal Achilles tendons with histologic correlation. Materials and methods: six tendon samples which were grossly normal on visual inspection and palpation were harvested. A 2D UTE pulse sequence was implemented on a 3T MR scanner and bicomponent and single-component T2* analysis was performed. Tendon samples were histologically processed and evaluated. Results: mean short T2* fraction was 79.2% (95% confidence interval [CI], 70.1–88.3%), mean short T2* was 1.8 ms (95% CI, 1.3–2.3 ms), mean long T2* fraction was 20.8% (95% CI, 11.7–29.9%), mean long T2* was 9.2 ms (95% CI, 5.1–13.3 ms), and mean single-component T2* was 2.5 ms (95% CI, 1.8–3.1 ms). Discussion: 2D UTE MRI with bi-component and single-component T2* analysis was successfully implemented. Inter-individual variation can be demonstrated in grossly and histologically normal Achilles tendons.

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