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A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas

  • Author(s): Perry, Arie
  • Phillips, Joanna
  • Venneti, S
  • Santi, M
  • Felicella, MM
  • Yarilin, D
  • Phillips, JJ
  • Sullivan, LM
  • Martinez, D
  • Lewis, PW
  • Thompson, CB
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4201755?pdf=render
No data is associated with this publication.
Abstract

© 2014, The Author(s).Pediatric glioblastomas (GBM) are highly aggressive and lethal tumors. Recent sequencing studies have shown that ~30 % of pediatric GBM and ~80 % of diffuse intrinsic pontine gliomas show K27M mutations in the H3F3A gene, a variant en

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