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High-bandwidth frequency-domain photon migration instrument for clinical use

  • Author(s): Madsen, S;
  • Anderson, ER;
  • Haskell, RC;
  • Tromberg, BJ
  • et al.

Published Web Location

https://doi.org/10.1117/12.209976Creative Commons 'BY' version 4.0 license
Abstract

We have developed a high-bandwidth frequency-domain photon migration (FDPM) instrument which capable of noninvasively determining the optical properties of biological tissues in near-real-time. This portable, inexpensive, diode-based instrument is unique in the sense that we employ direct diode laser modulation avalanche photodiode detection. Diffusion models were used to extract the optical properties (absorption and transport scattering coefficients) of tissue-simulating solution from the 300 kHz to 1 GHz photon density wave data.

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