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Ciliary Vesicle Formation: A Prelude to Ciliogenesis
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https://doi.org/10.1016/j.devcel.2015.03.012Abstract
Reporting recently in Nature Cell Biology, Lu et al. (2015) identify two Eps15-homology-domain-containing proteins as critical effectors of ciliary vesicle formation, an early event in ciliogenesis. Functional dissection reveals that one of them works to convert small vesicles associated with mother centriole distal appendages into a larger ciliary vesicle.
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