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A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells

  • Author(s): Shen, Yin;
  • Huang, K;
  • Xue, Z;
  • Bibikova, M;
  • April, C;
  • Liu, Z;
  • Cheng, L;
  • Nagy, A;
  • Pellegrini, M;
  • Fan, JB
  • et al.

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Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study, we analyzed DNA methylation patterns in a large number of hiPSCs (n = 114) and

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