Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
- Author(s): Devaraj, Sridevi
- Valleggi, Simona
- Siegel, David
- Jialal, Ishwarlal
- et al.
Published Web Locationhttps://doi.org/10.1007/s11883-010-0098-3
Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Low-grade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. This review outlines the role of high-sensitivity C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome by inducing endothelial cell dysfunction and activating monocytes.