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Open Access Publications from the University of California

Oncofertility in the setting of advanced cervical cancer - A case report.

  • Author(s): Gordon, Catherine
  • Carmichael, Joseph C
  • Tewari, Krishnansu S
  • et al.

Objective:To consider fertility options in women with advanced cervical cancer. Design:Case report. Setting:Large tertiary care center. Patient:A 30-year-old nulligravida woman diagnosed with FIGO Stage IBI squamous cell carcinoma of the cervix that had metastasized to a pelvic lymph node. Interventions:Robotic radical trachelectomy with pelvic lymphadenectomy and cerclage placement, followed by ovarian stimulation with oocyte retrieval and in vitro fertilization. Subsequent therapy included adjuvant chemoradiation and embryo transfer to a surrogate mother. Main outcome measures:Cervical cancer remission, live birth from surrogate pregnancy. Results:33-year-old woman in her third year of remission from advanced cervical cancer with healthy twin girls. Conclusions:Fertility options may exist for patients even in the setting of metastatic cervical cancer. Early involvement of a reproductive endocrinologist is imperative. This case emphasizes the importance of cross-specialty communication.

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