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Oncofertility in the setting of advanced cervical cancer - A case report

Abstract

Objective

To consider fertility options in women with advanced cervical cancer.

Design

Case report.

Setting

Large tertiary care center.

Patient

A 30-year-old nulligravida woman diagnosed with FIGO Stage IBI squamous cell carcinoma of the cervix that had metastasized to a pelvic lymph node.

Interventions

Robotic radical trachelectomy with pelvic lymphadenectomy and cerclage placement, followed by ovarian stimulation with oocyte retrieval and in vitro fertilization. Subsequent therapy included adjuvant chemoradiation and embryo transfer to a surrogate mother.

Main outcome measures

Cervical cancer remission, live birth from surrogate pregnancy.

Results

33-year-old woman in her third year of remission from advanced cervical cancer with healthy twin girls.

Conclusions

Fertility options may exist for patients even in the setting of metastatic cervical cancer. Early involvement of a reproductive endocrinologist is imperative. This case emphasizes the importance of cross-specialty communication.

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